Acyclovir and Hydrocortisone

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to using acyclovir and hydrocortisone if you have:
  • A weakened immune system, or get infections easily
  • Any allergies, including to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about any other medication you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Acyclovir and Hydrocortisone to learn more, including information on who should not use the drug.)

How Does Acyclovir and Hydrocortisone Work?

This medication is a combination of acyclovir and hydrocortisone. Acyclovir is an antiviral medication. It prevents the virus that causes cold sores (herpes simplex virus, or HSV) from multiplying. Hydrocortisone is a corticosteroid medication. It reduces inflammation, which can help relieve pain, swelling, redness, and itching.
Unlike most viruses, HSV is never completely removed from the body. Instead, it remains inactive in certain nerve cells, waiting to become active again. This is the reason cold sores come back. Acyclovir and hydrocortisone is not a cure for cold sores. It also will not prevent future outbreaks.

Acyclovir and Hydrocortisone Information

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