Megace ES and Pregnancy
Because Megace ES (megestrol ES) could harm an unborn child, this medication is not recommended for women who are expecting. Animal studies on this drug have shown that it might cause miscarriages, reduced fetal weights, and other problems. Women should use an effective form of birth control to avoid getting pregnant during Megace ES treatment.
Can I Take Megace ES When Pregnant?Megace® ES (megestrol ES) is a prescription hormone medication approved to treat loss of appetite, malnutrition, and significant weight loss in people with acquired immunodeficiency syndrome (AIDS). Megace ES is dangerous to an unborn child if taken during pregnancy and should not be used by pregnant women.
What Is Pregnancy Category X?The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Megace ES is classified as a pregnancy Category X medication.
Pregnancy Category X is given to medicines that show problems to the fetus in animal studies or in human use of the medication. With this category, the potential risks clearly outweigh the potential benefits.
Megace ES has not been adequately studied in pregnant women. However, in animal studies, the drug increased the risk for miscarriage and reduced fetal body weight when given in low doses to pregnant rats. The drug also appeared to cause male offspring to have female characteristics and impaired the ability of the male offspring to reproduce.
If you are a woman of childbearing potential, you should use an effective form of birth control to avoid becoming pregnant during Megace ES treatment. Also, let your healthcare provider know right away if you think you might be pregnant.