Yellow Fever Virus

The yellow fever virus -- the cause of yellow fever -- is a virus that is found in certain parts of Africa and South America. It is transmitted by mosquitoes, which can infect both humans and monkeys. Some of the countries where this virus is found include Chad, Ethiopia, and Burkina Faso.

What Is the Yellow Fever Virus?

The yellow fever virus is a flavivirus (virus transmitted by mosquitoes) that causes yellow fever.
 

Where Is It Found?

The yellow fever virus is found in certain parts of Africa and South America.
 
In South America, sporadic yellow fever virus infections occur almost exclusively in forestry and agricultural workers, from occupational exposure in or near forests. Countries where this occurs include: Bolivia, Brazil, Colombia, Ecuador, Venezuela, Guyana, French Guiana, and Peru.
 
In Africa, the yellow fever virus is transmitted in three geographic regions:
 
  • The moist savanna zones of West and Central Africa during the rainy season (most common)
  • Urban locations and villages
  • In jungle regions (to a lesser extent).
     
African countries where the yellow fever virus is located include:
 
  • Angola
  • Benin
  • Burkina Faso
  • Burundi
  • Cameroon
  • Cape Verde
  • Central African Republic
  • Chad
  • Congo
  • Côte d'Ivoire
  • Democratic Republic of Congo
  • Equatorial Guinea
  • Ethiopia
  • Gabon
  • The Gambia
  • Ghana
  • Guinea
  • Guinea-Bissau
  • Kenya
  • Liberia
  • Mali
  • Mauritania
  • Niger
  • Nigeria
  • Rwanda
  • São Tomé and Principe
  • Senegal
  • Sierra Leone
  • Somalia
  • Sudan
  • Tanzania
  • Togo
  • Uganda.
     

How Is the Yellow Fever Virus Transmitted?

Transmission of the yellow fever virus occurs in two main ways: urban (a mosquito bites an infected human) and sylvatic (mosquito bites an infected monkey).
 
Urban
Urban yellow fever virus transmission occurs when a mosquito bites an infected human. Once infected, this mosquito can then bite and infect another human. The infected mosquito can continue to pass along the yellow fever virus for its entire life. Aedes aegypti is the type of mosquito that normally transmits this urban type of yellow fever. This type of yellow fever virus transmission can lead to an epidemic of yellow fever disease. For example, in Brazil in 1973, at least 21,000 individuals out of 1.5 million people became infected with the yellow fever virus.
 
Sylvatic
Sylvatic yellow fever virus transmission occurs when a mosquito bites an infected monkey. Once infected, this mosquito will usually bite other monkeys; however, in certain cases, this mosquito can bite humans. This type of yellow fever virus transmission is more sporadic and usually only occurs in people that work within tropical rain forests. In East Africa, this mode of yellow fever transmission occurs through the forest canopy mosquito, A. africanus, which seldom feeds on humans.
 
(Click Transmission of the Yellow Fever Virus for more information.)
 
Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD
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